The spectre of another global health crisis looms large as the MPox virus continues its spread across the African continent. Mpox or monkeypox as it is commonly known is an infectious disease caused by the monkeypox virus. It can cause a painful rash, enlarged lymph nodes and fever. Most people suffering from it fully recover eventually, but some get very sick. ALSO READ: WHO calls for urgent action to address mpox surge in 17 African nations While the World Health Organisation has issued a clarion call for global support to contain this highly contagious disease, the onus of responsibility falls heavily on African nations currently grappling with the outbreak. Already, the disease has been reported in some 17 African countries. ALSO READ: EAC urges increased public awareness to prevent spread of ‘deadly’ Monkeypox The lessons of the Covid-19 pandemic are still painfully fresh. We witnessed firsthand the devastating impact of a virus left unchecked, and the critical importance of swift, decisive action. Most importantly, we witnessed how Africa was pushed to the back of the queue when it came to distribution of the Covid-19 vaccines largely because we sat and prayed for the magnanimity of the global north. We cannot afford to repeat these mistakes. It is imperative that we learn from the past and take proactive measures to contain MPox before it spirals out of control. While the WHO is advocating for increased funding to avail the vaccine, African countries must also shoulder the burden of raising the necessary resources to combat this threat. We cannot solely rely on external aid. A united front is essential to effectively address this crisis. By pooling our financial and human resources, we can expedite research, develop effective treatment protocols, and implement robust public health measures. Moreover, we must strengthen our regional health infrastructure and enhance surveillance systems to detect and respond to outbreaks promptly. Collaborative efforts to share knowledge, expertise, and best practices are crucial. By working together, we can build a resilient health system capable of withstanding future challenges. The time for inaction is over. Africa must demonstrate leadership and solidarity in the face of this crisis. By taking decisive action now, we can protect our populations, safeguard our economies, and prevent MPox from becoming another catastrophic health disaster. The future of our continent depends on it. Let us unite as one Africa and confront this challenge head-on. Finally, let us adequately fund pan-African research on such diseases to ensure we are better prepared for the future.