Comprehensive School Health Education (CSHE) is a multifaceted educational approach aimed at nurturing the overall well-being of young individuals within the school environment. This type of health education goes beyond traditional academic instruction, encompassing the physical, mental, social, and emotional dimensions of health. CSHE equips students with the knowledge and life skills necessary to make informed decisions about their health, emphasising areas such as nutrition, physical activity, mental health, sexual and reproductive health, alcohol and substance abuse prevention, and safety. This holistic approach fosters a supportive and inclusive school atmosphere, involving educators, parents, and the broader community in promoting healthy behaviours and positive youth development. By addressing the diverse aspects of well-being, CSHE empowers young people to navigate the challenges of growing up, promoting lifelong health and resilience. Africa as a whole is grappling with a myriad of health issues, from infectious diseases to malnutrition and the growing burden of non-communicable diseases. One powerful tool to mitigate these challenges is Comprehensive School Health Education. By integrating health education into the education system, we can equip the next generation with the knowledge and skills needed to make informed and healthy choices. Health education addresses various health aspects, including hygiene, nutrition, mental health, sexual and reproductive health, and substance abuse prevention, fostering a holistic approach to well-being. By educating young Rwandans on these and other topics, we empower them to lead healthier lives and make choices that reduce the risk of health problems in the future. CSHE also promotes a culture of prevention and wellness, which can significantly contribute to lowering the burden of disease in the long run, ultimately improving the overall health and quality of life for individuals and communities across the continent. When it comes to tackling the urgent health problems that young Rwandans confront, like mental health disorders, unwanted or early pregnancies, alcoholism and alcohol abuse, obesity, and non-communicable diseases among others, Comprehensive School Health Education can be an invaluable resource. Through the integration of CSHE into Rwanda’s educational framework, students could acquire the necessary information and life skills to address these ever growing challenges. CSHE provides a forum for fostering resilience and mental health awareness while instructing pupils or students on stress management and support-seeking techniques. By offering thorough sexual and reproductive health education, it lowers the chance of unwanted pregnancies and sexually transmitted infections. Additionally, CSHE highlights the significance of leading healthy lifestyles that include appropriate diet and exercise in order to fight obesity and lower the risk of non-communicable diseases in youth. In the recent past, much has been discussed on various strategies we can use to combat rampant alcohol use in youth. Health education can provide a structured framework for teaching risk behaviour prevention, particularly in addressing drug and alcohol use among the youth in Rwanda. Early health education incorporates evidence-based curricula that offer students accurate information about the dangers of alcohol or substance abuse, the physiological and social consequences, and strategies for making informed decisions. It encourages open dialogue and the development of life skills such as decision-making and effective communication, enabling students to resist peer pressure and make responsible choices regarding drug and alcohol consumption. Health education in schools could foster a supportive environment by involving teachers, parents, and the community in prevention efforts, reinforcing the message that drug and alcohol abuse can have detrimental effects on their future prospects, health, and well-being To effectively incorporate health education into youth learning in schools and universities in Rwanda, a comprehensive approach is essential. The curriculum could integrate age-appropriate and culturally sensitive health topics, such as nutrition, sexual health, mental well-being, and disease prevention. This can be achieved by collaborating with the Ministry of Health, Rwanda Biomedical Centre (RBC), local health experts and organisations. Teacher training programmes should emphasise the importance of holistic health education, equipping teachers and educators with the skills to deliver this knowledge effectively. Schools and universities can organise regular training or workshops, awareness campaigns, and extracurricular activities that promote healthy lifestyles. Encouraging student involvement in peer-led initiatives and community health projects can further reinforce the lessons learned in the classroom. Leveraging technology and online resources can help disseminate information and provide access to up-to-date health content. By taking these steps, Rwanda can foster a generation of informed and health-conscious youth. Early experiences, actions, and routines significantly impact long-term health. Experiences in the age of youth are the root cause of many adult health issues, including illness, depression, substance misuse, and more. Teaching the youth healthy habits and coping mechanisms is one of the best strategies to prevent illness in all of its manifestations. Entire health education can accomplish that. Dr Vincent Mutabazi is an applied epidemiologist. X: @VkneeM