More than 200 people have perished in devastating fires that gutted factories in Pakistan’s two largest cities, prompting calls for a review of work safety rules, officials said Wednesday.Around 194 people died at a garment factory in Karachi, in the worst inferno in decades to hit Pakistan’s Arabian Sea port and biggest city, just hours after 21 died at a shoe factory in Lahore, close to the Indian border.Dozens of others were hurt in Karachi as they jumped out of windows in the four-storey building to escape the blaze that began Tuesday evening in a bid to save their lives.Shouting and sobbing relatives of trapped workers, desperate to get inside the factory, scuffled with police overnight as rescuers battled to work through the night, an AFP photographer said."Three major hospitals in Karachi have so far received 194 bodies,” said provincial health minister Saghir Ahmed.Karachi fire chief Ehtesham Salim said dozens of bodies were found in the factory’s basement."We found dozens of people dead in a large room of the factory’s basement. It was totally burnt and parts of it were smouldering, which we put out before taking the bodies to hospitals.”Abdus Salam, a doctor at Karachi’s Civil Hospital, said bodies were badly burnt and that at least 65 other workers suffered broken bones after jumping out of windows to escape the flames.Salim called the factory dangerous, saying it had been flimsily built, lacked emergency exits and had developed cracks in the walls, which was also putting rescue workers at risk."It was packed like a box with little room left for ventilation. There were no emergency exits,” Salim said."We found people who died of suffocation caused by the highly toxic smoke. They died first and then their bodies were burned by the raging fire,” he said.According to workers, the factory produced underwear and plastic utensils.Salim said the disaster was Karachi’s "biggest fire in terms of deaths in decades”.In January 2009, 40 people were killed, more than half of them children, when a fire engulfed dozens of wooden homes in Karachi’s impoverished Baldia neighbourhood.  The garment trade is vital to Pakistan’s shaky economy.According to central bank data, the textiles industry contributed 7.4 percent to Pakistan’s GDP in 2011 and employed 38 percent of the manufacturing sector workforce. It accounted for 55.6 percent of total exports.