Antibiotic resistance now ‘global threat’, WHO warns

Resistance to antibiotics poses a “major global threat” to public health, says a new report by the World Health Organisation (WHO).

Tuesday, May 06, 2014

Resistance to antibiotics poses a "major global threat” to public health, says a new report by the World Health Organisation (WHO).

It analysed data from 114 countries and said resistance was happening now "in every region of the world”. It described a "post-antibiotic era”, where people die from simple infections that have been treatable for decades.

There were likely to be devastating implications unless significant action was taken urgently, it added.

The report focused on seven different bacteria responsible for common serious diseases such as pneumonia, diarrhoea and blood infections.

It suggested two key antibiotics no longer work in more than half of people being treated in some countries. 

One of them– carbapenem–is a so-called "last-resort” drug used to treat people with life-threatening infections such as pneumonia, bloodstream infections, and infections in newborns, caused by the bacteria K.pneumoniae.

Bacteria naturally mutate to eventually become immune to antibiotics, but the misuse of these drugs, such as doctors over-prescribing them and patients failing to finish courses - means it is happening much faster than expected.

The WHO says more new antibiotics need to be developed, while governments and individuals should take steps to slow the process of growing resistance.

In its report, it said resistance to antibiotics for E.coli urinary tract infections had increased from "virtually zero” in the 1980s to being ineffective in more than half of cases today.

In some countries, it said, resistance to antibiotics used to treat the bacteria "would not work in more than half of people treated”.

Gonorrhoea treatment ‘failure’

Dr Keiji Fukuda, assistant director-general at WHO, said: "Without urgent, coordinated action by stakeholders, the world is headed for a post-antibiotic era in which common infections and minor injuries that have been treatable for decades can again kill.”

He said effective antibiotics had been one of the "pillars” to help people live longer, healthier, and benefit from modern medicine.

"Unless we take significant actions to improve efforts to prevent infections and also change how we produce, prescribe and use antibiotics, the world will lose more of these global public health goods and the implications will be devastating,” Dr Fukuda added.

The report also found last-resort treatment for gonorrhoea, a sexually-transmitted infection which can cause infertility, had "failed” in the UK. It was the same in Austria, Australia, Canada, France, Japan, Norway, South Africa, Slovenia and Sweden.

More than a million people are infected with gonorrhoea across the world every day, the organisation said.

The report called for better hygiene, access to clean water, infection control in healthcare facilities, and vaccination to reduce the need for antibiotics.